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Meanwhile, the large hydrophobic side chain of Met338 in the mutant might make hydrophobic and van der Waals interactions with Asn313 and Phe314 from neighbor loop CD and thus may contribute to the conformational rearrangement surrounding the residues.
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The conspicuous absence of epithelial tumors in Pin1 null mice that carry mutant p53 raises the question whether epithelial cells have a special requirement for Pin1, which might make epithelial cancers particularly vulnerable to Pin1 inhibition.
"He might make a comeback.
You might make that argument.
It might make people squeamish.
— might make six-figure salaries.
Northwestern might make it someday.
That might make consensus easier.
That might make military sense.
It might make them nervous.
Might make right, in the street".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com