Sentence examples for murine colitis models from inspiring English sources

The expression of CHI3L1 protein clearly was detectable in lamina propria and colonic epithelial cells (CECs) in several murine colitis models and ulcerative colitis and Crohn's disease patients but absent in normal controls.

Separate serum and tissue models were generated for each of the murine colitis models.

All murine colitis models revealed bacteria in contact with the epithelium.

Failure of this protective barrier to separate bacteria from the epithelium is observed in a number of murine colitis models 15, 17.

However, the reduction in the anti-inflammatory bacterium Faecalibacterium prausnitzii, which is observed to occur in many human IBD studies, was not observed in murine colitis models.

In murine colitis models, IL-17A production from CD4+ T cells is protective because IL-17A directly suppresses the development of colitogenic Th1 cells via IL-17R expressed on activated CD4+ T cells (O'Connor et al. 2009).

This study was designed to investigate the effects of parthenolide on an experimental murine colitis model.

We evaluated the contribution of colonic inflammation to osteopenia and its mechanism in a murine colitis model.

Treatment with a HIF-1α agonist boosts the innate immune response of the intestinal epithelium in a murine colitis model [72].

Furthermore, conditional knockout of HIF-1α expression in intestinal epithelial cells exacerbated barrier injury and resulted in more severe symptoms in a murine colitis model [54].

Based on its anti-inflammatory properties and previous success in colitis studies, we investigated the effects of IFN-β in a murine colitis model.