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GATA4 is expressed as multiple transcripts with varying 5' ends encoded by alternative untranslated first exons.
Other GATA gene family members, however, are known to express multiple transcripts with different untranslated first exons (reviewed in [32]).
Consequently, genes using multiple promoters will generate multiple transcripts with 5′ TL heterogeneity.
This seems to be consistent with the recent finding that at least half of all human genes encode multiple transcripts with alternative 3' termini [ 30].
We used the same model as Figure 3 applied jointly to multiple transcripts with similar empirical mean expression levels μ m (0).
Two of the GST genes (GSTd1 and GSTs1) are alternatively spliced to produce multiple transcripts with identical N-termini but differing C-termini (see below).
Similar(53)
It was common for arrays to include multiple transcripts annotated with the same gene symbol.
This approach was applied for all such cases involving multiple transcripts associated with a given gene symbol.
Given multiple MAPT alternatively spliced exons leading to multiple transcripts, each with potentially different effects on function [ 1, 20], uncovering the precise regulatory change associated with genotypic variation in this region is critical.
This was, however, unusual, and in tissue-specific analyses (Additional Files 2, 3, 4, 7, 8 and 9), conflicts among multiple transcripts associated with the same gene symbol are indicated.
Where probes were annotated to multiple transcripts, the transcript with the longest 3'UTR sequence was selected.
Related(20)
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