Sentence examples for multiple susceptibility loci from inspiring English sources

The genetics of vitiligo cannot be explained by simple Mendelian genetics; it is characterized by incomplete penetrance, multiple susceptibility loci and genetic heterogeneity.

With an increased genetic understanding of migraine and the identification of multiple susceptibility loci [39], it is somewhat surprising that linkages to novel effective pharmacological targets such as CGRP [40 42] or its receptor are not identified.

Human GWAS studies in neurodegenerative diseases have now identified multiple susceptibility loci.

Multiple susceptibility loci of the ancestral strains demonstrate that SLE is inherited as a threshold trait.

The excess risk in those with a family history of PD may be conveyed by multiple susceptibility loci.

Many linkage studies of specific chromosomal regions and whole genomes in multiply affected families support the presence of locus heterogeneity, with multiple susceptibility loci 8– 10.

Genetic studies indicate the existence of multiple BiHM susceptibility loci [67].

Several of these immune diseases share multiple genetic susceptibility loci.

BATF overlaps rheumatoid arthritis and multiple sclerosis susceptibility loci at 14q24.3 (IMSGC et al., 2011; Stahl et al., 2010).

For example, a Type 2 Diabetes mellitus consortium performed GWAS in 8,130 Cases and 38,987 Controls and identified multiple novel susceptibility loci (23).

JRA is probably a collection of diseases with complex overlapping etiologies, with each subtype influenced by multiple genetic susceptibility loci and mediated by environmental effects [ 1].