Sentence examples for multiple susceptibility variants from inspiring English sources
Scott, L.J. et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
However not much is known about the genetic bases of PAD even though several GWAS for coronary artery disease have been completed and multiple susceptibility variants identified.
In contrast to Mendelian disorders that are usually caused by single gene defects and often manifest with serious physical and/or intellectual abnormalities without effective cures, predisposition to functional psychiatric illnesses is generally associated with multiple susceptibility gene variants with small to modest effects [32].
This integration of findings with relevance to the tested individual is especially important when multiple susceptibility genetic variants have been analysed.
We also found multiple independent susceptibility variants in the IL12B, NOS2, and IFIH1 regions.
38 However, for any complex disease, multiple common susceptibility variants, each contributing very modest effect sizes, should not be ignored.
For the remaining 11 complex regions, this study provides the first evidence for the presence of multiple independent PrCa susceptibility variants in close genomic proximity to one another.
This might suggest that the presence of multiple independent PrCa susceptibility variants within previously identified GWAS regions could be even more widespread than we have been able to identify in this fine-mapping study.
This raises the question of whether multiple common causative disease susceptibility variants within the same gene are responsible for the same ESKD phenotype, and whether they interact with each other.
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
International Multiple Sclerosis Genetics, C Genetics, Consortium, Beecham AH, Patsopoulos NA, Xifara DK, Davis MF et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
