Sentence examples for multiple susceptibility genes from inspiring English sources

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder with multiple susceptibility genes.

Psychiatric disorders are likely caused by multiple susceptibility genes, each with small effects in increasing the risk of illness [39].

Such a group or pathway level analysis potentially has more power to detect associations when a group containing multiple susceptibility genes each has modest evidence for association [61].

Type 1 diabetes (T1D) is an autoimmune disease resulting from the complex interaction between multiple susceptibility genes, environmental factors and the immune system.

In contrast, here we show that first ascertaining candidate co-adapted genes from population genomic data followed up by an association study is a feasible way to simultaneously detect multiple susceptibility genes for complex (disease) phenotypes even if these lack any individual effect on their own.

Recent GWASs have identified multiple susceptibility genes in sAD, including APOE, CLU, CR1 and PICALM.

In contrast to Mendelian disorders that are usually caused by single gene defects and often manifest with serious physical and/or intellectual abnormalities without effective cures, predisposition to functional psychiatric illnesses is generally associated with multiple susceptibility gene variants with small to modest effects [32].

We investigated multiple CD susceptibility genes in an Australian paediatric onset CD cohort.

TLE is currently considered to be a multifactorial disease, with multiple genetic susceptibility genes implicated and complex gene-environment interactions [5], [6] interplaying to determine disease onset and progression.

To analyze simultaneously multiple cancer susceptibility genes in one reaction.

The NOD strain carries multiple autoimmune susceptibility genes that provide a fertile background for several autoimmune syndromes.