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This method also accounts for the testing of multiple genetic models with each SNP.
The maximum tests were used to adjust p-value for multiple genetic models (So & Sham, 2011).
Relatively few programs are available for obtaining valid p-values when testing multiple genetic models.
In this study, we have examined seven polymorphisms for associations, using multiple genetic models, with risk of bladder cancer and cause-specific mortality following radiotherapy.
This variant was also associated with BMI in 760 Han Chinese adults (Fig 6D, p = 0.006 in dominant genetic model, corrected p = 0.007 for multiple genetic models, Supporting Information Table S1).
The success rates of ReliefF, SURF*, and SWRF* on synthetic data are plotted in Figure 2. The algorithms were evaluated on their ability to identify the two epistatic SNPs out of a set of 1000 noisy variables across multiple genetic models and replications.
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Our data that no significant correlation between ING2 expression and melanoma thickness or AJCC staging supports a multiple genetic change model during melanoma pathogenesis.
In the case of SNPs with multiple candidate best genetic models, the one with the smallest p value derived from the univariate Cox regression analysis was deemed to be the best genetic model [ 13].
Reversal of the chronic increases in wall stress by promoting SR calcium cycling can prevent and partially reverse heart failure progression in multiple genetic and acquired model systems of heart failure in both small and large animals.
Theoretical combined p is the p-value adjusted for multiple testing of different genetic models, obtained by the proposed analytic approach.
The format and open web access allows for importing new data from any disease-gene association study with multiple disease stages or genetic models of analysis.
Related(20)
multiple genetic systems
many genetic models
various genetic models
multiple transgenic models
several genetic models
numerous genetic models
multiple genetic loci
multiple genetic variants
multiple upcoming models
multiple numeric models
multiple logistic models
multiple genetic components
multiple genetic screens
multiple genetic differences
multiple genetic factors
multiple genetic traits
multiple experimental models
multiple genetic circuits
multiple nonnested models
multiple genetic conditions
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