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Notch is a transmembrane receptor that mediates cell-cell communication events in multiple developmental contexts [65], [66].
However, most of these gene families are used in multiple developmental contexts, making ancestral assignments impossible without more data.
Our data indicate that these genes play opposing roles to the pocket protein ortholog lin-35 /pRb in multiple developmental contexts.
Ttk69 is known to regulate both cell proliferation and cell cycle in multiple developmental contexts (Badenhorst, 2001; Jordan et al., 2006).
Besides functioning in mature nervous system to regulate synaptic specificity in both invertebrates and vertebrates (de Bivort et al., 2009; Alberi et al., 2011), Notch has also been found to act in the post-mitotic neurons in multiple developmental contexts.
Our current study uncovers a previously underappreciated functional link between these two cytoskeleton systems and demonstrates that this link is physiologically important for regulating the Hippo pathway in multiple developmental contexts.
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This feature of enhancers may be especially important in developmental contexts where multiple family members that have different activities are co-expressed, resulting in potential competition for TF binding to shared sites.
A key feature available in the mirEX 2.0 database is the integration of NGS sRNA-seq data into graphical expression plots along with the RT-qPCR-based transcript level measurements in the context of multiple developmental stages and tissues.
While overall tubulin expression is carefully controlled, most eukaryotes express multiple tubulin genes in specific regulatory or developmental contexts.
The ability of a cell to accurately respond to external signals in different developmental contexts relies on the integration of multiple sets of signaling pathways, which in many cases are highly conserved through evolution.
Moreover, precise temporal control afforded by a small molecule could prove to be critical for functional dissection of BMP signaling in complex biological contexts like organogenesis, where BMP pathway function at multiple developmental nodes with often divergent effects.
Related(20)
many developmental contexts
various developmental contexts
multiple experimental contexts
several developmental contexts
multiple developmental relationships
multiple cellular contexts
multiple medical contexts
multiple fuzzy contexts
multiple developmental ages
multiple controlled contexts
multiple metabolic contexts
multiple developmental processes
multiple temporal contexts
multiple developmental domains
multiple other contexts
multiple virtual contexts
multiple developmental roles
multiple developmental defects
multiple developmental trajectories
multiple fragmented contexts
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