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Our results provide a platform for disentangling the role of space and spatial control in multiple cellular contexts and a basis for engineering spatial control in signaling cascades through localization/compartmentalization.
These results, obtained in multiple cellular contexts using both reporter activation and AKT phosphorylation status, strongly suggest a role for PALD in insulin-induced AKT phosphorylation.
In the present study, we investigated the dependency of AR on FOXA1 expression in tissue paraffin sections, in multiple cellular contexts, and on tumor-bearing nude mice.
Dvl and Par1b form a protein complex in multiple cellular contexts, prompting us to investigate the mutual dependency of Par1b and Dvl3 for Smad4 association.
Cell adhesion-cell migration was among the most predominant GO categories in each tissue type, indicating a conserved role for Twist1 in cell adhesion-migration in multiple cellular contexts.
Of note, Kunkel et al. studied the potential regulatory role of miR-199a-5p miR-199a-5p miR-199a-5pinied SRF as its upstreamyogenesisr through computandonal programs and experidentifiedlidation, SRFgesting thas the SRF/mits199a-5p regupstreamaxis might be involved in multiple cellularegulators.
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β-Catenin plays important roles in multiple cellular and disease contexts but much remains to be learned about the regulation of β-catenin in the different cellular contexts, including pivotal ones in the human central nervous system.
Because there are many different types of proteases that can operate in various cellular contexts, multiple experimental approaches for their degradomic characterization had to be developed.
In mouse, it is expressed widespread in various types of tissues and organs, suggesting its multiple roles in different cellular contexts (Wang et al. 2015).
THBS1 is a large, homomultimeric extracellular matrix glycoprotein with multiple signaling functions in different cellular contexts.
Extensive genetic analysis of the interactions between sel-11 and multiple lin-12 alleles in different cellular contexts established sel-11 as a negative regulator of lin-12 activity, but its molecular identity was not determined [8].
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multiple cellular compartments
multiple medical contexts
multiple fuzzy contexts
multiple cellular processes
multiple experimental contexts
multiple controlled contexts
multiple metabolic contexts
multiple temporal contexts
multiple cellular pathways
multiple developmental contexts
multiple cellular proteins
multiple other contexts
multiple cellular sites
multiple virtual contexts
multiple cellular systems
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