Sentence examples for multiple developmental defects from inspiring English sources

Sanford, L. P. et al. TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes.

Deficiency of both Akt1 and Akt2 resulted in multiple developmental defects including muscle atrophy [13].

Previous reports have shown that CXCR4-null mice exhibit multiple developmental defects and die perinatally [3], [4], [29].

In contrast, Trp73 knockout mice (which lack all p73 isoforms) exhibit multiple developmental defects but no tumor predisposition [13].

Previously, mouse models for histone methyl transferases and histone demethylases have been characterized with multiple developmental defects [31] [33], [62].

Mice with Akt1/Akt2 deficiency develop multiple developmental defects and severe muscle atrophy, indicating that both Akt isoforms contribute to the determination of muscle size.

In contrast, disruption of both Sulf1 and Sulf2 simultaneously resulted in high-penetrance perinatal lethality in conjunction with multiple subtle developmental defects.

This indicates that the obtained gene expression profiles of later stages of ERK2 morphants (6hpf and 8hpf) are the results of a prolonged epiboly arrest, most likely due to multiple secondary developmental defects (Fig. 2 and 3).

Loss of viability was associated with multiple, although subtle, developmental defects, including skeletal and renal abnormalities.

Human hydrocephalus is a heterogeneous disorder with multiple etiologies including genetics, developmental defects, viral infection, tumors, hemorrhage and advanced age [ 1- 3].

But in many taxa, fertilization of eggs by multiple sperm (polyspermy) results in developmental defects.