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There are multiple challenges with heterogeneous ADCs including analytical challenges, batch-to-batch consistencies, the stability of the ADC, and the potential for variable pharmacokinetics if conjugation sites in some antibodies interfere with normal FcRn-mediated recycling (Beck et al., 2017).
Multiple challenges with coalition work must be overcome before success is achieved.
Almost two-thirds of these children faced multiple challenges, with 64percentt presenting with both medical and mental health conditions.
There are multiple challenges with translating the promising in vitro studies with bacteriophages to widespread clinical use.
Caregivers reported that they face unique and multiple challenges with their loved ones due to the ongoing decline exhibited in AD.
Yet the clinical development of therapies targeting the FGFR signalling pathway presents multiple challenges, with diverse mechanisms of pathway activation combined with multiple inhibitors of differing potency and with antibodies in preclinical development.
Similar(54)
Together, the studies presented herein, cover novel research, tools, and approaches focusing on overcoming the multiple challenges associated with the quantification and analysis of ES bundles, trade-offs, and synergies.
Due to the multiple challenges associated with this technology, field trials are strongly recommended before the direct application of the process on a large scale.
School nurses encountered multiple challenges including limitations with communicating instructions and follow-up with the parents/guardians.
(Married man, aged 58 years, Keraniganj, Dhaka, focus group discussion) Many community members preferred to seek health care from informal CTC health service providers because of the multiple challenges they faced with formal providers and the easy access and availability of informal CTC health service providers in their locations.
While there are several potential advantages with these reactors, they are also confronted with multiple challenges.
Related(20)
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