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ORFs that include GH10 or GH11 xylanase modules commonly showed multiple catalytic modules.
Some of the catalytic components possessed diverse hydrolytic activities ranging from exoglucanases (CelS, CbhA, CelK) to endoglucanases (CelA, CelF, CelN, CelB), xylanases (XynA/U, XynY, XynZ), and other hemicellulases (LicB, ChiA), and some proteins contained multiple catalytic modules (CelH, CelJ).
This revealed the presence of multiple catalytic modules in xylanases [19], [20], [21] and the presence of non-catalytic dockerins [19], [22] and of substrate-binding modules [23] in both cellulases and xylanases.
Thus for the six completed ORFs that include a GH5 module, and the four completed ORFs that include a GH9 module, these were the only identified catalytic module present, as opposed to some examples of multiple catalytic modules that occur in GH9 and GH5 enzymes of the Clostridium thermocellum cellulosome.
Such enzymes may contain single or multiple catalytic modules (GH) together with single or multiple noncatalytic carbohydrate-binding modules (CBMs) [ 10].
They include: non-complexed enzymes with single catalytic domains, independent single peptide chains incorporating multiple catalytic modules, and complexed, scaffolded structures, such as the cellulosome.
Similar(54)
These species accomplish plant biomass degradation by producing an arsenal of extracellular carbohydrate degrading enzymes [ 4, 7, 8] that include cellulases with multiple catalytic enzyme modules in a single multi-domain enzyme.
Complex multi-modular organization, involving multiple catalytic and substrate-binding modules within the same polypeptide, has been documented previously for plant cell wall degrading enzymes, especially xylanases, from the related strain R. flavefaciens 17 [20], [21], [22], [22].
Multifunctional enzymes refer to proteins that consist of two or more catalytic modules.
The GH catalytic modules corresponding to 11,010 sequences were the most predominant and represented 96 different families altogether.
ALDHs have multiple catalytic and non-catalytic functions in addition to their roles in aldehyde metabolism [19].
Related(20)
several catalytic modules
multiple catalytic cycles
multiple catalytic capabilities
multiple biological modules
multiple catalytic sites
multiple catalytic regions
multiple catalytic activities
multiple simple modules
multiple catalytic enzymes
multiple catalytic events
multiple theoretical modules
multiple catalytic centers
multiple catalytic strategies
multiple catalytic properties
multiple smart modules
multiple catalytic functions
multiple catalytic pathways
multiple catalytic reactions
multiple catalytic subunits
multiple catalytic devices
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