Sentence examples for multiple cardiac defects from inspiring English sources

As we have shown previously, FOG-2 deficient mice die at approximately embryonic day 13.5 due to multiple cardiac defects that include ventricular septal defects and ventricular wall hypoplasia [18], [19].

Whereas mutant mice for Hey2 (also known as CHF1, Herp1, Hrt2, Hesr2 or gridlock in zebrafish) show no obvious vascular abnormalities with multiple cardiac defects [4] [6], compound Hey1; Hey2 mutant embryos have impaired arterial-venous specification [7], [8], similar to those seen in mutant mice for Notch receptors and ligands, including Dll4 [9]–[11].

HDAC2 knockout mice are viable but present fatal multiple cardiac defects.

In 28.9% (n = 60) of the children, there were multiple cardiac defects (i.e. a combination of defects).

For example, most SRp38 knockout embryos die before E15.5 with multiple cardiac defects [ 25], whereas a small number of mutant mice are born only to die soon after birth [ 22].

The term Q p is the average pulmonary flow obtained by taking an average of QASD (atrial septal defect flows) over multiple cardiac cycles.

Multiple individual ADAM isoform KO mice display cardiac defects, including Adam 9, 17, and 19 [66], [67], [67].

In addition to somatic mutations, germline mutations in BRAF have recently been identified as causing CFC syndrome, a multiple congenital anomaly disorder whereby individuals have characteristic craniofacial dysmorphisms, cardiac defects, ectodermal anomalies and developmental delay [18], [26].

Pax3 is required in multiple developing systems and mutations also cause neural tube [12] and cardiac defects [13], which can lead to the death of homozygous mutants in utero from embryonic day E14 [14].

For example, FKBP12-/ mice suffer early embryonic death due to cardiac defects, and the disruption of genes that encode for the nuclear-localized FKBP42 and FKBP70 leads to multiple morphogenetic defects in Arabidopsis thaliana [ 12, 13].

Some studies suggest an association between S.S.R.I.s and certain types of infant cardiac defects (while another study has correlated S.S.R.I.s with a lower incidence of certain cardiac defects).