Sentence examples for mouse strain used from inspiring English sources

Humans might vary more in their response to the drug than the inbred mouse strain used in these experiments, she points out.

The CD177 knockout mouse strain used for this research project was created from ES cell clone (12120a-B11), obtained from the KOMP Repository (www.komp.org) and generated by Regeneron Pharmaceuticals , Inc(Valenzuela et al., 2003).

Here we emphasize the importance of accurate dose selection in rodent anxiety paradigms for concluding whether the mouse strain used is "sensitive" and therefore appropriate for studying anxiety in selected behavioral tests.

Our own data have already hinted towards a strong dependence of splenic tracer uptake on the respective mouse strain used [31], whereas tracer uptake in human LNCaP xenografts accurately reflects the respective expression density of human PSMA and thus allows valid comparisons [13, 25, 30, 32].

The main mouse strain used in this study was C57BL/6 (Harlan, Israel).

The analysis of Cre mediated recombination depends on the reliability of labelling in the reporter mouse strain used.

Total RNA was extracted from ~250 islets of each mouse strain using the Qiagen RNeasy Mini Kit (Qiagen, Hilden, Germany).

To disrupt the Mena gene in mice, we generated a mouse strain, using the RRG138 embryonic stem (ES) cell line from BayGenomics (http://www.genetrap.org).

Tamoxifen-inducible Cre recombinase was PCR-amplified using genomic DNA purified from tail biopsies of the CAG-CreESR1 moustrainain using Phu polymerase (Thermo Fisher Scientific, Waltham, MA).

The inbred mouse strains used in this study were Balb/c, C57BL/6, C3H/HeJ and DBA/1J.

Muscle, spleen and pancreas thymidine concentrations were measured in non-tumour-bearing mice in the PC and SCID mouse strains used at the CI (Fig. 3).