Sentence examples for mouse strain engineered from inspiring English sources

The researchers tested their idea with a mouse strain engineered to lack the GT gene.

Probing this further, Abner Notkins and his colleagues at the National Institute of Dental Research in Bethesda, Maryland, studied the effects of pregnancy hormones on a mouse strain engineered to express several HIV-1 genes.

To assess the role of NM23-M1 and NM23-M2 in melanoma progression in vivo, we have crossed [ m1m2]+/− mice with a transgenic mouse strain engineered for overexpression of hepatocyte growth factor (HGF+).

However, a recent study demonstrated infection, replication and de novo virus production in an inbred mouse strain engineered to express human HCV entry factors in the liver and carrying a targeted lesion within innate immune signalling genes (Stat1, Irf7, Irf9, IFN-αβR).

The ubiquitous expression of truncated p53 protein isoforms, results in "premature ageing" of laboratory mouse strains engineered for expressing such isoforms.

The generation and characterization of the Xeno-Mouse-G2 strains, engineered to produce fully human IgG2 antibodies, were described by Mendez and coworkers [ 31].

Recently, a mouse strain was genetically engineered to knockdown the expression of Cox-2 [32].

We investigated chromatin organization in the heterozygous F1 genotype Df/+  D Bl 6. Df is the chromosome 4 from the 129S5/SvEvBrd mouse strain with an engineered 4.3 Mb deletion in 4E2 [ 19] (Fig.  2b).

Here we study neurons derived from a genetically engineered mouse strain with a truncating lesion disrupting the endogenous Disc1 ortholog.

We have tested this hypothesis by generating and analyzing a genetically engineered mouse strain in which theN-methyl-d-asparate (NMDA) receptor gene is ablated specifically in the CA3 pyramidal cells of adult mice.

This was accomplished by using in vivo fluorescence imaging of LysEGFP mice, a genetically engineered mouse strain that possesses green-fluorescent neutrophils [47], [48].