Sentence examples for mouse mutants are from inspiring English sources

Genetically engineered mouse mutants are valuable tools to elucidate the genetic control of behaviour and the interaction between genetic and environmental factors.

Ercc1 mouse mutants are also more sensitive to the prototypical PD toxin MPTP, and their transcriptomic landscape shares important similarities with that of PD patients.

The majority of new mouse mutants are therefore designed as conditional, activated only in a specific tissue (spatial control) and/or life stage (temporal control) through biogenic Cre/loxP technologies.

In mouse, mutants are known for both the ligand, Eda-A1 (Tabby), and the receptor, Edar (Downless).

In addition Eif2ak2 knock-out mouse mutants are more susceptible to influenza infections [ 36, 37].

Mouse mutants are a valuable tool for identifying novel pathways underlying specific neurological phenotypes and exploring the influence both genetic and non-genetic factors.

Gene engineering for generating targeted mouse mutants is a key technology for biomedical research.

The generation of targeted mouse mutants is a key technology for biomedical research.

The development and standardisation of sensitive, valid behavioural tests which are suited to phenotype mouse mutants is both a responsibility and a challenge to investigators of mouse behaviour.

Behavioural phenotyping of mouse mutants is not a goal in itself but serves to characterise the behavioural effects of naturally occurring or experimentally induced mutations.

The other model was generated by Cre/lox-mediated neuron-specific inactivation of the Prkg1 gene using the Nes-Cre line [22]; these mouse mutants were termed Prkg1 brain knock-out mice (Prkg1BKO mice; see Fig. 1A and methods section).