Sentence examples for mouse model thus from inspiring English sources

MiR199b-5p exprespecificallyimpairsimpairs the cancer-stem-cell (CD133+) population, which results in vivo in impairment of MB tumor development in the cerebellum xenograft mouse model, thus providing proof of concept.

To approach conditions encountered by these bacteria during human infections, further studies were performed during exposure to urine, in a peritonitis mouse model and in a mouse bacteremia mouse model thus leading to the identification of new genetic determinants putatively involved in the pathogenic potential of Enterococcus faecalis.

This mouse model thus provides unprecedented opportunities and tools to investigate further the pathogenesis of retinal degenerative disease and to identify new therapeutic targets for medical intervention.

Unfortunately, the lead compounds identified in this study also demonstrated significant plasma instability in a mouse model thus raising doubts on their in vivo usefulness.

In the present study, PCF successfully decreased the levels of cytokines and restored Treg/Th17 balance in the asthma mouse model, thus improving airway inflammation and reducing asthma symptoms.

Some research groups have already developed various NEK2A inhibitors, which have been shown to effectively suppress tumor growth in xenograft nude mouse model; thus the outlook on this field appears promising.

However, such pathways have not been validated in HD mouse models thus far.

Importantly, we and others have identified altered transcriptional control and aberrant localization of transcripts encoding many of these genes in FASD mouse models, thus making them suitable candidates for the current study [ 36– 36].

CCl4 administration induces hepatic injury and jaundice in a mice model, thus simulating a condition of acute hepatitis and hepatotoxicity.

We speculate that this may be due to the minimal use of transgenic mice models thus far.

Furthermore, 20 displayed a robust antitumor activity in a breast cancer xenograft athymic mouse model and thus promoted to the lead rank.