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The differential expression in the laterality organs of zebrafish and mouse may explain the different role that this transcription factor plays in controlling LR laterality and symmetric somite formation in these two vertebrates.
Its absence in mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
Its absence in the mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
Our data suggest that the truncated PPARα splice variant functions as an endogenous inhibitor of proliferative and pro-inflammatory genes in human cells and that its absence in mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
Based on our studies, we suggest that the truncated PPARα splice variant provides protective mechanism in acting as an endogenous inhibitor of proliferative and pro-inflammatory genes in human cells and its absence in mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
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Widespread hepatic infection in susceptible mice may explain how they both produce increased amounts of infectious virus and induce dysregulated coagulation pathways.
Widespread hepatic infection in susceptible mice may explain how these animals both produce increased amounts of infectious virus and induce dysregulated coagulation pathways.
Higher blood cyanide levels in male vs. female mice and in MAN- vs. AN-treated mice may explain the gender-related differences in the toxicity of these chemicals and the greater potency of MAN vs. AN.
New research on mice may explain this behavior: Nicotine spurs the production of a key neural protein that's scarce in schizophrenics--and that may help relieve their symptoms.
Therefore, decreased leukocyte activation in infected CCR2 /– mice may explain the decreased cytokine storm and decreased tissue damage observed in these animals.
Reduced expression of specific serotonin receptors and serotonin transporter, as recently reported in pre-motor symptomatic R6/1 mice, may explain this abnormal serotoninergic pattern [32].
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