Sentence examples for mouse may phenocopy from inspiring English sources

It is likely that JNK1-deficiency and JNK2-deficiency in the mouse may phenocopy the effects of MKK4 gene mutation on breast cancer in humans.

We surveyed the literature to catalog Aβ PTM including species with isoAsp at positions 7 and 23 which may phenocopy the Tottori and Iowa Aβ mutations that result in early onset AD.

The pathological similarity suggests that epigenetic processes may phenocopy the Familial Alzheimer's disease (FAD) mutations within sporadic AD.

For example, ablation of Fgfr2-IIIb and its mesenchymal derived ligand Fgf10, result in failure to form lungs and submandibular (salivary) glands, indicating that the switch in Fgfr2 isoforms in Esrp DKO mice may be sufficient to phenocopy these defects, but not others.

These mouse mutants phenocopy many features associated with human individuals that harbor UPD for the syntenic region of chromosome 14.

10.7554/eLife.02676.004 Figure 2. R111G mice phenocopy the null mice whereas R111G Tg mice are indistinguishable from WT mice.

Thus, consistent with the interaction between Tex19.1 and Ubr2, these two mouse null mutants phenocopy each other.

Genetically engineered mouse models that "phenocopy" the human disease can help decipher MYC's role in transformation and progression in a given lineage/cell type [36], [40].

How closely does progerin mimic the normal aging process and are there alternative strategies that may better phenocopy the aging process?

FRAS and FREM mutations found in individuals with FS (or in the blebs family of mouse mutants that phenocopy the disorder) lead to defects in epidermal adhesion and the formation of large skin blisters in utero.

Areg knockout (KO) mice phenocopy ER KO mice as ablation of either gene results in severely impaired ductal development during puberty (Bocchinfuso et al., 2000; Mallepell et al., 2006; Ciarloni et al., 2007).