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Microinjecting the acetylcholinesterase inhibitor neostigmine into the pontine reticular formation of C57BL/6J (B6) mouse causes a rapid eye movement (REM) sleep-like state.
Transplantation of the C26 tumor to a host mouse causes a significant loss of body weight and muscle mass and closely reproduces the clinical features of cancer-induced muscle wasting [7], [15].
TRN activation in an awake mouse causes a cortical single unit to become phase-locked to the induced slow waves.
Furthermore, loss of Pin1 function in the mouse causes a range of abnormalities due to defective cell proliferation and differentiation.
Targeted disruption of prosaposin in the mouse causes a complex neurodegenerative phenotype resulting in a severe leukodystrophy with accumulation of GSLs in both neurons and microglial cells (23).
Here, we show that somatic deletion of Nrbp1 in the mouse causes a progenitor cell phenotype that disrupts the normal programme of cellular differentiation and proliferation along the intestinal crypt villus axis.
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She clicked her mouse, causing a virtual scalpel to lay the pig's kidney open, its internal regions highlighted by blinking labels.
And she often finds problems like tendinitis because people aren't supporting their arms when they use a mouse, causing a tighter grip and increasing muscle tension.
The paralog Zfhx1a (a.k.a. Zeb1) when knocked out in mice causes a cleft palate phenotype with 100% penetrance [59], [60].
In summary, this study demonstrated that an additional Fas deficiency in ApcMin/+ mice causes a dramatic increase in the number of intestinal tumors.
The lack of Rab27a in Ashen mice causes a defect in vesicle tethering to the PM, as well as in exocytosis of LG [18], [20], [22].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com