We demonstrate here that administration of GI264879A to rats causes a significant decrease in food intake and body weight partly through a mechanism dependent on the integrity of the vagus nerve.
There is a difference in the effects of smaller and larger particles, but this, for a release scenario during a major accident, is only of low relevance [34 39] Nano-ZnO Medium Low 1 1 Application of micro- or nanoscale ZnO particles into the lungs of mice or rats causes a strong but intermediate inflammatory reaction.
For example, lack of maternal care in rats causes a significant effect on brain gene expression and stress related behaviour later in life [1].
We therefore hypothesise that the amplified and prolonged neonatal leptin surge in OffOb rats causes a similar down-regulation, leading to inhibition of leptin's neurotrophic actions and permanent leptin resistance.
Experimental id or subcutaneous (sc) injection of the plague agent into laboratory rodents, e.g. guinea pigs, mice and rats, causes a disease similar to naturally acquired bubonic plague [6] [12].
The chronic administration of N-2-acetylaminofluorene (N-2-AAF) to rats causes a loss of hepatic cytoplasmic RNA, particularly from the endoplasmic-membrane fractions.
Reduction of MyH7B in rats causes a profound alteration in dendritic spine structure and excitatory synaptic strength (Rubio et al. 2011).
Particularly, we determined that post-MI remodeling in middle-aged female rats causes a much greater accumulation of interstitial and especially perivascular collagen than in males.
A single injection of testosterone into neonatal female rats causes a higher uptake of P in adult life, while a single injection of oestradiol into male neonates lowers the incorporation in adult life.
Indeed, metformin administration to rats causes a change in the composition of the microbiome (Pyra et al., 2012), although it remains unclear what effect this has upon the host.
