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Each mouse represents a scientifically updated version of a deadly sin: the snarling representative of anger is said to be pumped up on testosterone; an immensely fat glutton has been given an extra gene for obesity.
The successful regeneration of human ear-shaped cartilage using a tissue engineering approach in a nude mouse represents a promising approach for auricular reconstruction.
The βENaC-Tg mouse represents a murine model with CF-like lung disease that mimics an imbalance of CFTR-mediated anion secretion and ENaC-mediated Na+ absorption characteristic of human CF airways.
These pathological findings closely mimic the CEP disease in humans and demonstrate that the Urosmut248 mouse represents a suitable model of the human disease for pathophysiological, pharmaceutical, and therapeutic purposes.
Thus, the Id1−/− mouse represents a model that simulates the bone and BM features seen in an aged host.
The CD11c-eYFP reporter mouse represents a valuable tool for the efficient detection of endogenous dendritic cells by two-photon microscopy[19].
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The NOD/Scid eGFP mouse represents an advanced animal model for long-term xenotransplantation studies with primary human biopsies.
The ACDase-deficient mouse represents an important addition to a growing number of mouse models that have genetic defects affecting sphingolipid metabolism (Sabourdy et al, 2008).
On the basis of our findings, the Mwk mouse represents an ideal system to investigate the intrinsic factors that link altered calcium signaling and Purkinje cell development.
The P. yoelii pre-erythrocytic infection of the mouse represents an accepted model closely reflecting human malaria (Luke and Hoffman, 2003).
K/BxAg7 mice also develop cardiac valvulitis, another feature occurring in RA. 10 Thus, the K/BxAg7 mouse represents an ideal animal model to examine the influence of inflammatory arthritis on the development of atherosclerosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com