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This signal contains sufficient information to detect motion and to select image information of the different acquisitions to either produce one motion corrected data set for morphologic imaging without patient compliance or to perform a detailed motion analysis [85].
PVEC was applied to the motion corrected data using the region-based voxel-wise (RBV) method [2] and regions of interest (ROIs) defined from the MPRAGE images using FreeSurfer and the measured point-spread function [3].
We chose to analyze the uncorrected rather than the motion corrected data.
Three-dimensional motion corrected data can be refraction corrected and processed for more accurate biometry measurements unaffected by alignment errors or motion artifacts when acquiring only a single cross-sectional OCT image.
As head motion influences iFCMRI [ 36], motion corrected data were obtained from the scanner software (syngo MRVA30A, Siemens, Erlangen, Germany) that provides a 3-dimensional elastic motion correction in all directions.
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A registration algorithm using orthogonally scanned OCT volumetric data sets which can correct motion on a per A-scan basis is applied to compensate motion and merge motion corrected volumetric data for enhanced OCT image quality.
Then several nuisance covariates were regressed out from the motion corrected fMRI data, including the mean signals of white matter and cerebrospinal fluid, six rigid motion parameters and their first-level derivatives.
This manuscript presents a software based OCT motion correction algorithm which can correct motion in three dimensions and on a per A-scan basis and enables merging motion corrected volume data to enhance the OCT signal quality without requiring a motion free reference image or additional hardware on the OCT instrument.
(GIF 5 MB) 40658_2014_7_MOESM2_ESM.gif Additional file 2: FDG PET motion animation for PET- driven attenuation corrected data set.
Then, the corrected data are reconstructed a final time into a cardiac-phase series of images to capture the heart's beating motion.
The two motion corrected 3D OCT data sets are then merged to create a motion corrected 3D data set with improved SNR [ 22].
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