Sentence examples for most active isoform from inspiring English sources

In the large GST family, GSTA4 is the most active isoform in catalyzing conjugation of GSH to 4-HNE [ 4].

Previously, using in vitro systems reconstituted with purified enzyme, CYP2C19 was the most active isoform for methoxychlor- O-demethylation.

VEGF 165 (165 amino acids) is the predominant, biologically most active isoform and is referred to as VEGF in this review.

IL-32 has four splice variants, IL-32α, IL-32β, IL-32δ and IL-32γ, with IL-32α as the most abundant transcript, and IL-32γ as the most active isoform.

We next determined whether FGF8 is sufficient to induce Atoh1 expression by using a full-length mouse Fgf8b, the most active isoform of Fgf8 which accounts for the majority of isthmic FGF function (Sato et al., 2001; Guo et al., 2010).

The scarce use of the most active, ancestral isoform may suggest that the emergence of exon 12a in chordates could have been associated with increasingly strict regulatory control of Meis target genes.

VEGF165 the predominant and most biologically active isoform was measured in this study.

AKR1C4 is the most catalytically active isoform for DHT reduction in human [ 28] and has high expression in mammary tissue.

It has been shown that CYP2E1 is one of the most active CYP450 isoforms in generating intracellular ROS [ 26] and oxygen radicals are associated with cancer development and metastasis [ 27].

However clinical trials on the effectiveness of dietary supplementation with vitamin E or α-tocopherol, the principle and most active vitamin E isoform in human plasma, as an aid in the prevention of cancer have not produced evidence of a consistent association with decreased cancer occurrence [ 4, 5].

For example, the M2 isoform of pyruvate kinase PKM2, which is the isoform most active in malignant tissue, is acetylated at one of its lysine residues, K [58].