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Exact(6)
In contrast, AS2-treated cells had large numbers of IMV (Figure 9C and 9F), reminiscent of morphological defects seen following IMCBH treatment [88], [89].
The AS1 inhibitor morphological block appeared reminiscent of morphological defects seen with the vaccinia redox proteins, A2.5, E10, G4, phosphoprotein A13 and LY294002 pretreatment [20], [22], [26], [28], [48].
Those sperm that were present showed the same morphological defects seen in animals where canonical secretion had been reduced.
Several examples of severely abnormal morphology were observed (Fig. 4A-D), although these did seem to be distinct from the morphological defects seen in (simw ); OreR (Fig. 3C,D).
Importantly, neither P ama1 - myoa nor P ama1 - mtip ookinetes had the morphological defects seen in the CDPK1 knockdown lines, and both were able to bend and twitch, although neither could glide.
These findings were also consistent with the lack of gross morphological defects seen in fbn-1 single mutant embryos as well as mec-8; sym-3 or mec-8; sym-4 double mutants, which nevertheless had a prominent keyhole and Pin phenotype.
Similar(54)
However, unlike Drp1 mutants, Marf mutant NMJs exhibit severe morphological defects (see below).
However, when the p53 MO was co-injected with the ewsr1a MO or the ewsr1b MO, the morphological defect seen in the brain with the ewsr1a or ewsr1b MO alone was rescued, indicating that the morphological defects in the CNS induced by knock-down of ewsr1a and ewsr1b were mediated by the P53 pathway (Figure 5, compare d to e and f to g).
This construct failed to efficiently rescue the morphological, apoptosis and proliferation defects seen in the mutant, confirming the importance of clathrin binding (Fig. 8A C).
The specificity of the nuclear morphological and higher-order chromatin organization defects seen in crwn mutants reveals the interplay between nuclear morphology and the three-dimensional packaging of the genome.
We therefore examined lungs of E17.5 Crem−//−, Crem−/− double transgenic mice and looked for potential morphological defects in addition to the already-described defects seen in the E17.5 Creb1−/− lung.
Related(15)
morphological abnormalities seen
morphological deficiencies seen
molecular defects seen
morphological variants seen
morphological patterns seen
morphological results seen
morphological findings seen
morphological defects displayed
morphological phenotypes seen
morphological differences seen
morphological specializations seen
morphological changes seen
morphological features seen
morphological blocks seen
morphological alterations seen
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