Sentence examples for molecular defects seen from inspiring English sources

These findings may be explained by limited experimental suppression of LIN28B and MYCN, the fact that neither CH1 nor A2780 cell lines faithfully phenocopy all of the molecular defects seen C5 tumours, and the amplification of HMGA2 in CH1 cells.

Human tissue is of limited availability, cell culture commonly does not express the molecular defects seen in tissue, and no animal models exist that accurately reflect human POLG encephalopathy syndromes.

Mitochondrial deficiencies, and alterations in melanin granule number and distribution dominated the defects seen in PE.

Thus, the defects that we observe in thymocyte number and thymic architecture are consistent with defects seen under stress conditions.

The 12 defects seen on the acetabular side were five segmental defects (AAOS type I), two cavitary defects (AAOS type II) and five combined defects (AAOS type III).

Whether the sluggish movement defect seen in adult apl-1 knock-down worms is due to the molting defect, starvation or a neurotransmission defect remains to be seen.

These defects are not as severe as the defect seen in a rad9Δ mutant.

The pathologic plasma cell in AL amyloidosis is thought to be similar to the plasma cell seen in multiple myeloma, with common molecular defects.

To better assess changes in gene expression seen in our data, we conducted a comprehensive literature search on molecular defects of apoptosis in pancreatic cancer.

"They're willing to take some risks and see some projects fail," says advisory board member Brian Druker of Oregon Health & Science University in Portland, who helped develop Gleevec, a model for drugs targeted at molecular defects in cancers.

XP patients bear molecular defects either in nucleotide excision repair (NER) or in translesion synthesis (TLS).