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We can search for larger effect sizes by studying more homogeneous sub-populations, for example, those defined by (i) more specific phenotypes (e.g. early onset cases), or (ii) familial cases of the disease.
More specific phenotypes may hold greater promise in the study of genetics in hand OA.
The manuscript is more appropriately specific about phenotypes, having dispensed with "adult onset" and "superficially wild-type" in favor of more specific phenotypes.
However, the in vivo function of the peptides might lead to more specific phenotypes, as their expression pattern in the plant might be local, and not correlate with the ectopic application of active peptides as performed in the assays.
Our analysis also supports phenotyping on the basis of osteophyte severity and a joint-specific approach, as more specific phenotypes may hold greater promise in the study of the genetic basis of hand OA.
Similar(55)
Consequently, a more specific phenotyping would be necessary to identify specific cases in which auditory neurons are less damaged.
However, the behavioral effect we have observed is no doubt just part of the phenotype attributable to Comt1 but, but without more specific phenotyping of higher cognitive functions and behavioral analysis in both male and female mice, our results should be considered preliminary.
Classifying the disease into different, more specific clinical phenotypes and biological endotypes is the first step to a more individually tailored and effective therapy for children suffering from asthma [9].
Without a doubt, cancer is largely driven by genome dysfunction, frequently exemplified by specific genetic alterations that drive one or more specific cancer phenotypes (Hanahan and Weinberg, 2011).
This effort, known as the consilience project, sought to highlight both better animal models for these areas, as well as better-defined and more specific human phenotypes to target.
New technologies will provide information on numerous biomarkers, which may help us distinguish more specific dementia phenotypes, but we need strong measurement tools to better take advantage of these data.
Related(20)
more precise phenotypes
more differentiation phenotypes
more specific questions
more specific moves
more specific exceptions
more exclusive phenotypes
more different phenotypes
more similar phenotypes
more specific details
more Myc phenotypes
more specific differences
more common phenotypes
more dramatic phenotypes
more specific goals
more specific nouns
more specific yolks
more divergent phenotypes
more homogenous phenotypes
more extreme phenotypes
more specific instructions
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