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In addition, the SNP-CC analysis may help to assess a risk in infected individuals for the progression to HUS and to implement more specific infection control measures.
More specific infection of the uterine mucosa by intrauterine inoculation with human chlamydial strains, as previously described [42], might lead to a more coherent outcome.
Moreover, information about the SNP-CC may help implement more specific infection control measures and may enable a risk assessment for each detected EHEC O26 isolate.
Of the 24 case reports (11.3%) with multiple infections, 12 (50%) reported a nonspecific infection term, such as "infection" or "URTI," combined with a more specific infection term, such as "nasopharyngitis" or "cystitis" (see the Supplementary Data for a summary of the infections according to the MedDRA lower-level term).
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We also created three composite outcomes: hospitalized for pneumonia, vascular access infection, or sepsis or infection-related death (a more specific infection-related composite outcome); hospitalized for any infection or use of intravenous antibiotics (a more sensitive infection-related composite outcome); and cardiovascular hospitalization or cardiovascular-related death.
Wearing specific protective clothing (aprons or waterproof shoes) among LPTs was generally widespread, but may be more related to protecting clothing, because compliance to more-specific infection-control hand-washing and wearing gloves was, at best, only moderate.
PCT, very expensive and more specific for infection, should complement the common serologic tests only when there is the clinical suspicion of infection.
Recently several biomarkers, namely procalcitonin (PCT), have been described as more specific in infection diagnosis.
Procalcitonin (PCT) appears to be more specific for infection and, unlike CRP, its levels appear to reflect severity and prognosis.
Radiolabeled white blood cell (WBC) imaging is more specific for infection; however, it lacks anatomic spatial resolution, limiting ability to separate soft tissue from bone involvement (6– 8).
However, increasing evidence suggests that variability in the patterns of physiologic measures may be more specific for infection and may be an earlier indicator of sepsis than standard diagnostic criteria [ 20- 23].
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