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These they defined as (1) products that result in the substantial reduction in exposure to one or more tobacco toxicants and (2), if a risk reduction claim is made, products that can reasonably be expected to reduce the risk of one or more specific diseases or other adverse health effects.
Many other more specific diseases would be expected to follow adverse outcomes for these health measures (see Discussion section).
An association between literacy and multimorbidity may exist when two or more specific diseases individually related to health literacy coexist in one person.
It should also be noted that small number of daily mortality in some communities might lead to imprecise risk estimation, and for this reason we only examined the effects on mortality from respiratory and cardiovascular systems; further studies on more specific diseases are warranted in future studies.
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Thus, several relatively nonspecific biomarkers can be combined in order to provide a more specific disease index.
Development of new psoriasis treatments targeting more specific disease mechanisms has therefore remained a research priority [6].
Gene Ontology (GO) analysis established that highly-connected proteins are likely to be engaged in higher level GO biological process terms, while low-connectivity proteins tend to be engaged in more specific disease-related processes.
This suggested that visual memory fitted a more specific disease precursor model than verbal memory, a finding compatible with Skelley et al's study [5] showing that visual memory impairments were present in schizophrenic patients but absent in their non-affected adult relatives.
Therefore, adopting a more specific disease focus, in combination with dedicated disease ontologies, will better empower the selection of comparable studies with refined annotations to address the research question at hand.
This compression of the more specific disease terms is undesirable at MGI where a distinction is defined between mouse models with similar or differing etiology compared to the human disease.
Use of more specific disease codes for identifying AMI during drug use may lead to a small but significant change in risk estimates and at the expense of decreased precision.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com