Sentence examples for more small molecules from inspiring English sources

The first is that we can detect many more small molecules as mass spectral signals in biological samples than we can presently identify [129], possibly as a result of unknown enzyme promiscuity [130 132].

Controlled release of one or more small molecules is the keystone of nerve communication, and these small molecules are the nervous system's neurotransmitters, typically stored in small synaptic vesicles that are released at synapses specialized structures incorporating a presynaptic neuron nerve and a postsynaptic target cell.

In general, bacterial spores germinate in response to the binding of one or more small molecules, and the small molecules that can cause germination vary among different species and strains of bacteria [13].

LINCS expands CMap by including more small molecules, genomic perturbations, cellular contexts and treatment parameters.

This network approach provides a hypothesis-testing framework for explaining similarities between any two or more small molecules based on the biological processes to which they are connected in the network.

In addition, it was recognized that in the future more small molecule-containing databases might reside at EMBL-EBI, either because existing databases may begin to annotate their data with chemical information, or because entirely new resources are developed or adopted.

"In 20 years, biotech companies will be doing more small-molecule work than large-molecule," Dr. Levinson said.

Whereas big pharma does more small-molecule research, the biotech industry focuses on the cause of the problem, what's actually going on inside the body.

Two FGFR inhibitors, namely AZD4547 and BGJ398, have entered phase II clinical trials, while more small-molecule inhibitors, such as SU5402, PD173074, TKI-258, and SU6668, have failed in clinical trials due to various complications associated with the side effects caused by the ATP-competitive inhibition mode [ 8].

Several PSMA-directed radiolabeled agents have been developed, including monoclonal antibodies, antibody-fragments, minibodies, and more recently small molecules.

To develop more potent small molecules with enhanced free radical scavenger properties, we designed and synthesized a series of nitronyl nitroxide derivatives 4a h.