This can be explained by the concept that "flexible" molecule of ethanedithiol is bonded to activated polymer surface by both of -SH groups, while the more "rigid" molecule of biphenyldithiol is grafted only via one of -SH groups and the second one is "free" for chemical reaction with Au nanoparticle.
Thus, a gel made from a more rigid molecule will have a longer equivalent segment length and, thus, for the same cross-link density will be correspondingly stiffer and less extensible.
Such firming is due to changes in the molecular status of the starch, specifically to a kind of aggregation of sections of the long-chain molecules into micelles, making the molecules more rigid and less soluble than in the newly gelatinized granule.
This can indicate two populations: T22 is very close for both materials and can be assigned as the less restricted parts of the molecules; T21, on the other hand, is the more rigid part of the molecules, where OA is more restricted than MO (due to smaller values).
The branching functionality of the micelles played an important role in the solubilization process: for copolymers of similar composition, the solubilization capacity and rate were lower for higher generations, presumably due to the more rigid structure of the molecules.
The more rigid parts of the molecule should receive more weight, the flexible ones less.
For F146W, we observed that E2 decreases (43 cm–1) and E3 increases (144 cm–1), indicating that the inner-layer water molecules become more rigid after DNA binding as reflected by the increase in the relaxation times from 6.3 to 7.4 ps and from 103 to 192 ps and corresponding slower solvation speeds.
This molecule is more rigid and much less active than AT1 non-peptide mimetic losartan probably because it lacks to mimic the orientation of tetrazole and the pharmacophore segments of butyl chain and imidazole ring.
At the same time, the two helical regions also exhibit intensity enhancements, thus it is probably that the entire molecule becomes more rigid.
