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Some studies of a commercial PCR test for influenza showed a relatively low sensitivity (∼75%); the authors suggest the use of a more sensitive reference test to confirm negative results.
In order to show further improvements in imaging, we need a more sensitive reference standard.
The authors claim that the PPV is even higher when a more sensitive reference test was used.
An index test compared against a more sensitive reference test (microscopy with multiple measurements) may have higher specificity because the number of false-positives will be low.
An index test compared against a more sensitive reference test (higher quality) may have higher specificity because the number of false-positives will be low.
Similar(53)
This implies that the results of dynamic analysis are more sensitive with reference to period determination for the UHS than current CHBDC in short period range.
Newer technologies can often provide increasingly sensitive diagnostic tests; however, there is no straightforward method to evaluate their performance when they are more sensitive than the reference standard.
Preschool children were significantly more sensitive in the with-reference than in the no-reference condition, but the magnitude of this anchoring effect was smaller than that observed in adults.
A slope of >1 shows that the reaction under study is more sensitive to substituents than the reference reaction, while a slope of <1 shows that it is less sensitive.
Although massively parallel sequencing technologies achieve dramatically higher throughputs than capillary sequencing, the ability of the short read lengths to map uniquely to a reference sequence is more sensitive to base calling errors.
With MRI or US as reference, FOI was more sensitive than CE.
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Justyna Jupowicz-Kozak
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