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Over the years, more stringent reference levels of 150 Bq m−3 or less have been proposed by international institutions and national agencies.
However, the magnitude of this risk was modest (OR = 1.43) and decreased rather than increased with use of more stringent reference groups excluding those exposed to secondhand smoke.
Firstly, we have not undertaken any independent verification of the accuracy of injury diagnoses within SHR although we have shown that our estimates for cruciate ligament injury are quite consistent with studies using more stringent reference standards [ 24].
Further, in none of the studies reviewed, in either the peer-reviewed literature or the JMPR database, was it evident that the human data contributed to a lower (more stringent) reference value than that based on animal data; rather, the converse was true - human data, if they influenced a reference value at all, led to a relaxation of the value.
Use of a more stringent reference group did not increase the smoking risk ratios in part because of the limited number of women who had no active or passive smoke exposure and the lack of an association between secondhand smoking and breast cancer in this sample.
Similar(52)
In Weining, Qingzhen, and Leigong, average exposures remained below provisional tolerable weekly intakes for total mercury and for methylmercury (0.57 μg/kg/d and 0.23 μg/kg/d, respectively) and a more stringent methylmercury reference dose of 0.1 μg/kg/d.
We further divided euthyroid type 2 diabetic patients into two subgroups (TSH: 2.0 to <4.0 vs. 0.4 to <2.0 μIU/ml) and compared the two based on a more stringent "normal" reference interval of TSH suggested by the National Health and Nutrition Examination Survey NHANESS) III (7).
These findings suggest that a longer, more comprehensive neuropsychological battery may be a more stringent and appropriate reference test.
Thus, more stringent filtering of the reference genome was required.
Therefore, to get more stringent results, only one reference genome was kept for each species or subspecies (the genome with the highest percentage of coding DNA sequences covered by reads).
Because a more stringent manual review of reference sequences, as performed in diagnostic practice (14 ), was not feasible for this large study, the 673 isolates detected by this algorithm represent a conservative estimate of the total number of novel species encountered.
Related(20)
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