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A more positive fluid balance was associated with a more prolonged length of stay in the ICU and in the hospital.
Disease severity on admission was directly correlated with older age, more prolonged length of stay, and presentation during the two epidemic waves seen in the observation period.
Patients in Group 2 had more prolonged length of stay in the ICU and in hospital than patients in Group 1.
We must underline the fact that our study reported an independent association, not a cause-effect relation between more prolonged length of storage of RBC units and outcome in critically ill patients: only a randomized clinical trial on this question may prove that such cause-effect relation is real.
In 2007, Perianayagam and colleagues found a +242 C/T polymorphism (rs4673) in the pro-oxidant enzyme NADPH (Nicotinamide Adenosine Dinucleotide Phosphate) oxidase p22phox gene T-allele, associated with more prolonged length of hospital stay, higher dialysis use, and higher odds for composite outcome [ 28].
Similar(55)
Despite the use of maximum RBC age to define old RBCs, which biases our results towards the null hypothesis, our analysis indicated a significant independent association between RBC unit length of storage and both the occurrence of new or progressive MODS and a more prolonged PICU length of stay.
B-NP patients had a more prolonged mean ICU length of stay after pneumonia onset than NB-NP patients (28.5 ± 30.6 days vs. 20.5 ± 17.1 days, P = 0.03) (Table 2).
We report an independent association between more prolonged RBC unit length of storage and increased morbidity: patients who are transfused with at least one RBC unit stored for 14 days or longer had a significantly higher risk of new or progressive MODS and a longer PICU length of stay.
Following a coronary angioplasty, patients from more deprived areas were more likely to have had a prolonged length of stay (aOR = 1.66, 95% CI: 1.25-2.20).
As expected, the experimental group had more risk factors (e.g., prolonged length of stay before enrollment, previous VAP).
Those from the most deprived areas were 1.7 times more likely to have a prolonged length of stay of over 1 day.
Related(20)
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