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While the initial concept of the Vallesian Crisis considered it as an abrupt event44 and relevant changes have been observed in both macro- and micromammal faunas7,20,32, during the last years several authors have suggested that it could really be a succession of extinctions during a more prolonged time interval7,24,27,32.
Patients with AKI received vancomycin for a more prolonged time period (14.9 ± 9.8 vs. 9.2 ± 4.9 days; p = 0.05).
Thus, by increasing further the [PO4 3-] up to 50 mM, biomass seems to come on at a higher value after a more prolonged time of cultivation.
However, after a more prolonged time in the state of torpor labelling extended further away from the cell body into the band of Bechterew.
Paradoxically, because of more prolonged time and less intensive administration, the number of CMF cycles fared better among patients who received concomitant radiotherapy.
The rest of the resistance patterns remained fairly stable, possibly indicating that a more prolonged time period is required to have an impact.
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Second, because the study was designed to examine acute effects, we could not assess more prolonged time-dependent effects of exposures (McDonnell et al. 2007) or effects resulting from sequential rather than concomitant exposures.
The benefits of the controlled delivery of drugs include: the maintenance of serum drug concentration at an optimal therapeutic level for a more prolonged time-interval, reduction in handling and consequently, a possible improvement in drug-administration compliance [ 38].
Insulin glargine revolutionized the diabetes therapy by being the first soluble long-acting insulin analog without a pronounced peak and with a more prolonged time-action curve than NPH insulin (1– 4).
Possible benefits conveyed by one sedative regimen over another may become evident over a more prolonged time-course as both IL-6 and apoptosis were reduced by dexmedetomidine but not midazolam.
Therefore, contact with these combinations of active compounds might be more prolonged in time and widespread in the environment than previously assumed.
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more prolonged duration
more prolonged hospitalization
more prolonged blockade
more prolonged exposure
more prolonged intermittent
more prolonged downturn
more prolonged slump
more prolonged help
more prolonged abstinence
more prolonged fever
more prolonged war
more prolonged stimulation
more prolonged inhibitory
more prolonged abstention
more prolonged clino-rotation
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