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Exact(9)
We suggest that because more polymorphic loci, presenting higher mutation rates than average, were selected during marker development, the calculated upper bounds of the ranges may be overestimates.
There is a fine line between adding more polymorphic loci and having that addition variation being less reliable.
Polymorphic loci identified by pairwise comparisons between N2 and CB4856 were selected at random and satisfied the criteria of two or more polymorphic loci within 300-500 bp.
A haplotype block consists of two or more polymorphic loci (e.g. SNPs) in close proximity, which tend to be inherited together with high probability.
At the same time, however, more polymorphic loci increase the risk of overestimating external pollen flow by increasing the error rate.
9 The isolated strain was typed by using mycobacterial interspersed repetitive unit (MIRUs), and locus-specific PCRs for the four more polymorphic loci (1, 5, 9, 33) were used to differentiate the isolated strain.
Similar(51)
Assuming that within-locus variations in repeat length are mainly due to mutations representing small changes in repeat number [ 62, 63], large differences in allele sizes (∆ al) from 9930 and Gy14 suggest that these loci have higher mutation rates and are more polymorphic than loci with small ∆ al values.
Presumably the same clustering patterns would remain if the samples were analyzed at thousands of genome-wide SNPs that have not been selected for their polymorphism - i.e. presumably more, less polymorphic loci should show the same substructure.
It is obvious from both studies [ 8, 10] that there is a need for a much more detailed investigation of these the two biphyletic taxa based on many more autosomal polymorphic loci.
By adjusting cut-off values for the number of repeat units toward a lower boundary, we discovered more polymorphic MS loci that are both highly polymorphic and can be uniquely identified in the genomes.
However, there were 4.5 times more polymorphic SNP loci in pistachio than in lupin, this is probably owing to the high heterozygosity level of plant materials used for our study; we used an F1 population in a dioecious species whereas the lupin studies used a RIL population.
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