Sentence examples for more favourable conformation from inspiring English sources

Furthermore, we thought that display on albumin could present Q14 in a more favourable conformation for cross-linking than when it is present in a short peptide.

This may be due to 2-naphthyl derivative occupying the hydrophobic cavity in a slightly more favourable conformation than compound 21.

Previously, we reported efforts at replacing the ester with an amide, but this led to loss of activity; possibly due to the amide causing a conformational change compared to the ester.[ 5] In this paper, we report the effect of cyclising the ester to form a fused pyridone, which might lock the compound into a more favourable conformation.

In view of our obtained data, which could mean that the increased amount of α2,3-linked sialic acids in C4-2B cells are in a more favourable conformation than the sialic acids in LNCaP cells allowing for a better interaction with the neutral carbohydrate moiety of AsGM1.

The better KD values for the antibody species on fixed cells suggests that the antigen, when expressed on the cell surface, exists in a more favourable conformation than that of the GST-MUC1 fusion protein or 60-mer peptide absorbed to a plastic surface or immobilised onto a Carboxy-Methyl dextran chip.

For GalNAc derivatives, sulfation in the 4th position does not make any significant effect, while sulfation in position 6 makes the tg conformation significantly more favourable.

The free energies of both conformations of +139 C were slightly more favourable than those of the +139 U conformations.

Hence, the direct interaction between the clamp and the exonuclease does not only enhance the interaction between the Pol III and the clamp, but also positions the exonuclease in a conformation that is more favourable for DNA access.

Interestingly contribution of internal energies to the free energy was very significant for Leu941, this indicates that final conformation of Leu941 is more favourable upon binding to H3K4me3 and H3K9me3 peptides.

This result suggests that, although the active-site lid can sample at least two distinct conformations, the closed form is presumably a more favourable, lower free-energy state.

In our case, we calculated that the conformation of Ltri is 11 kcal/mol more favourable than that of Lbi.