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Women are more easily infected.
The mutant far more easily infected human immune cells than did the ancestral pseudotype, the team reports today in Cell.
The present results with prepupae show either a greater virulence by the Iranian strain or increased pupal susceptibility, which lacking larval mobility and grooming behaviors, would be more easily infected by the IJs.
This is the first work to demonstrate clearly that the PBMC monocytes obtained from G6PD-deficient patients, using an ex vivo culture system, were more easily infected with the two DENV-2 strains-(1) the New Guinea C strain from the DF patient or (2) the 16681 strain from the DHF patient than with those from healthy controls.
This is particularly important for girls, who are more easily infected with HIV during sex than boys.
Third, the inner mucosal surface of the prepuce, which has a high density of HIV target cells (CD4+ T-cells, Langerhans cells, macrophages), has been shown to become more easily infected with HIV as compared to outer foreskin tissue [ 45].
The researchers also showed that the mutant more easily infects primate cells than cells from rodents or carnivores.
But scientists are concerned that the virus might adapt to more easily infect people.
For years, leading scientists around the world have worried that large-scale, indoor swine "factories" would become breeding grounds for new pathogens that could more easily infect humans and then spread out rapidly in the general population - threatening to become a global pandemic.
He goes on to say that "scientists around the world have worried that large-scale, indoor swine 'factories' would become breeding grounds for new pathogens that could more easily infect humans and then spread out rapidly in the general population -- threatening to become a global pandemic".
In addition, if related parasites more easily infect hosts with similar ecologies and if chemical, physiological and ecological characters in part covary with phylogeny, false conclusions can arise from cophylogeny analyses.
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Maria Pia Montoro
Terminologist and Q/A Analyst @ Translation Centre for the Bodies of the European Union