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DBI is a 10-kDa polypeptide that was first isolated by monitoring its ability to displace diazepam from the benzodiazepine (BDZ) recognition site located on the extracellular domain of the GABAA receptor and on the mitochondrial membrane (Guidotti et al., 1983; Costa and Guidotti, 1991).

The chaperone-like activity of PDC-109 was assayed by monitoring its ability to prevent heat-induced aggregation of aldolase at 48°C [23], [27].

The activity of superoxide dismutase (SOD, EC 1.15.1.1) was assayed by monitoring its ability to inhibit the photochemical reduction of nitroblue tetrazolium (NBT).

The activity of superoxide dismutase (SOD) was assayed by monitoring its ability to inhibit the photochemical reduction of nitroblue tetrazolium (NBT).

We tested the ability of UvrD1 647 to function in NER in vivo by monitoring its ability to restore UV-resistance to a strain that lacked chromosomal uvrD.

To verify this, we immunoprecipitated endogenous WNK1 and WNK3 from wild-type and knockin ES cells and assessed its activity by monitoring its ability to phosphorylate OSR1 in vitro.

Similar(54)

In this series, compound 52 was identified as the most potent QC inhibitor with an IC50 value of 58 nM, which was two-fold more potent than the previously reported lead 2. Compound 52 is a most promising candidate for future evaluation to monitor its ability to reduce the formation of pGlu-Aβ and Aβ plaques in cells and transgenic animals.

To study adaptive responses to environmental changes without signal transduction machinery, we constructed a synthetic gene network that can exhibit bistability and monitored its ability to switch between two stable attractor states in response to evnironmental change.

To complement the in vitro binding assays, we tested a representative coiled-coil construct in mammalian cells and monitored its ability to interact with endogenous IKKβ.

CRIS is evaluated regularly to monitor its masking abilities and also to highlight any drawback in de-identification that may occur over time (e.g. new styles of recording PIs, technical glitches, or procedural failures).

The Milan-based Hacking Team claims that it monitors its software, and has the ability to disable functionality if it believes that clients "have used Hacking Team technology to facilitate gross human rights abuses".

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