Physical measurements using a breathing thermal manikin were taken to identify its ability to provide clean air to inhalation depending on design, shape, size and positioning of the ATD, flow rate and temperature of personalized air, room temperature, clothing thermal insulation of the manikin, etc. Tracer gas was mixed with the room air.
Although it was originally identified by its ability to inhibit G1/S progression in human fibroblasts, its role as tumor suppressor is debated.
It was also identified for its ability to confer resistance to antimicrobial peptides produced by plants (Ibeas et al. 2001; Tanaka et al. 2007) and animals (Gank et al. 2008).
It is notable that an antibody identified by its ability to block heat-induced polymerization of native Z α1-antitrypsin in vitro also blocked polymer formation in a cell model of disease.
Indeed, the yeast LARS2 equivalent, LeuRS was not originally identified by its ability to aminoacylate its cognate tRNA, consistent with it having developed multiple functions.
Further study of this tetraspanin is required in OED to identify its true prognostic ability.
The oncogenic potential of TBX2 was first identified by its ability to bypass cellular senescence in a Bmi −/− mouse embryo fibroblast model9.
A murine monoclonal antibody was identified by its ability to induce a reversible antiproliferative effect on a human lymphoma cell line.
BBI608, a small molecule identified by its ability to inhibit gene transcription driven by STAT3 and cancer stemness properties, can inhibit stemness gene expression and kill stemness-high cancer cells isolated from a variety of cancer types.
An azoreductase was initially identified by its ability to break the azo linkage during the dye metabolism under aerobic and anaerobic conditions (Zimmermann et al. 1984; Rafii et al. 1990).
