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Our results suggest that similar to phosphorylation, acetylation of Hsp90 on multiple residues controls its ability to chaperone distinct client proteins.
9, 10 EGFR exists in an equilibrium that controls its ability to transition from an inactive to an active state and vice versa.
The effector α-ketoglutarate binds to PII and controls its ability to activate its receptors (reviewed in refs (1) and (21)).
Overall, these findings suggest that KDAC regulation of Hsp90 controls its ability to chaperone a distinct set of clients, similar to Hsp90 regulation by phosphorylation (Mollapour et al., 2010, 2011).
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These include the regulatory genes named tat, rev, nef and vpr, which are all thought to regulate the speed by which HIV is able to replicate itself, and the "accessory" genes vif and vpu, which are less well understood, but believed to control its ability to infect people.
But scientists don't know whether the lizard actively controls its clinging ability using fine muscle movements in its feet or whether its feet are just intrinsically sticky.
is monitoring site is located in the Rotterdam city center and is subject to frequent quality control to ensure its ability to represent urban background air pollution.
By last week, the London mayor was talking about the "tragedy" of a union that he argued was stifling democracy and had stripped Britain of its ability to control its borders and its trade policy.
As the candidates fan out to New York and California and here to the heartland, they are confronting an electorate that is deeply unsettled about the United States' place in the world and its ability to control its own destiny.
Second impact syndrome is when another blow to the head (even a minor one) results in the brain losing its ability to control its own blood flow, which may result in rapid and potentially fatal brain swelling.
Its treatment of the detainees is emerging as a pivotal test of both the provisional government's commitment to the rule of law and its ability to control its thousands of loosely organized fighters.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com