Sentence examples for molecules which interfere from inspiring English sources

The development of small molecules, which interfere with pathogenic protein-protein interactions underlying neurodegenerative diseases.

The main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with pathogenic protein-protein interactions underlying neurodegenerative diseases.

This is achieved through the secretion of effector molecules which interfere with the innate immune system resulting in the pathogen remaining "hidden" from the plant.

Direct inhibitory molecules, which interfere with the TGF-signalling pathway, have been described including Sno or Ski or more recently Akt (Conery et al, 2004; Remy et al, 2004).

A promising approach is seen in molecules, which interfere in the signal transduction of B-cell receptors (e.g. ibrutinib) and therefore present an attractive therapeutic option for B-CLL and B-cell lymphoma [ 67, 68].

Inflammatory cytokines particularly enhance bone loss by activation of osteoclast differentiation factors such as MCSF and RANK ligand and by molecules which interfere with bone formation such as DKK1 and sclerostin.

The excitement generated by targeted drugs, which interfere with specific molecules involved in tumour growth and suppression, has been short-lived.

There is NO role in our diets for foreign molecules such as trans fats and high-fructose corn syrup, which interfere with our biology at every level.

Bagasse was extracted with water and ethanol prior to treatment since better mass balance closures are obtained by removing non-structural molecules which can interfere with characterisation of solid and liquid fractions.

On the other hand, IGFBP5 is thought to be associated with proteins of the extracellular matrix (ECM) like fibronectin depending on bound molecules, which might interfere with IGF1 and further growth activities [ 46, 49].

They demonstrated that a drug called ibrutinib, which interferes with the signalling molecule BTK, produced impressive remissions in patients with C.L.L.