Sentence examples for molecules which represent from inspiring English sources

In some cases there are very few molecules which represent inhibitors of a particular target.

Here we reconstruct by transmission electron microscopy and single particle image reconstruction method the three dimensional arrangement of two neighbouring RrgB molecules, which represent the minimal repetitive structural domain of the native pilus.

Evidently they need to be informed that also naturally occurring statins contain pharmacologically active molecules which represent a (low) possibility of side-effects [ 23].

Small PrP aggregates comprising 14 28 PrP molecules, which represent only a minor proportion of total hamster PrP, have specific infectivities ∼70-fold higher than large PrP aggregates [ 40].

Expression of these co-stimulatory molecules, which represent an important part of the bridge between the innate and adaptive arms of the immune response, is governed by the adapter TRAF6 (Kobayashi et al., 2003), and also involves CD40 ligation, antigen presentation and co-stimulation (Fujii et al., 2004).

For 10 000 non-cognate molecules (each covering 46 bp) 460 000 bp of the DNA will be covered by non-cognate molecules, which represents 10% of the entire DNA.

In the other extreme, for 50 000 molecules, 2 300 000 bp of the DNA will be covered by non-cognate molecules, which represents 50% of the entire DNA.

It has therefore become routine practice for some researchers to call the dominant type, the "major molecule", which represents the LH variant that is most abundant in a DNA extract.

All 5 metrics rely on the so-called accumulation curve, Fa k), where the subscript "a" stands for active molecule, which represents the count, possibly normalized, of how many true binders obtained a rank better or equal to a given one in a docking run; Fa(k) contains all the information needed to assess the performance of a run, and a combination of multiple runs as well.

Also very prominent is the category of references related to MHC molecules (18.1%), which represent important targets, either as a whole protein, or as a source of allorecognized peptides.

We describe herein (i) the development of a panel of complementary and improved miniaturized high-throughput screening and profiling assays, which we believe will have broad appeal to other investigators, and (ii) the identification of novel small molecule APE1 inhibitors, which represent initial chemotypes in the long-term endeavor of creating new targeted pharmaceuticals.