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Such findings are in excellent agreement with previous observations that molecules in cellular membranes can remain mobile under certain, relatively mild PFA fixation conditions [12].
If there is a barrier to diffusion at any given location, it will require a longer time to find the particle at a position across the barrier, as demonstrated for the diffusion of molecules in cellular membranes [19].
Recently, circuit diagnosis techniques have been utilized to identify the most vulnerable molecules in cellular networks [ 31].
While the roles of adhesion molecules in cellular recruitment have been partially defined [15], their relative abilities to mediate binding of antibody-conjugated inert particles is unexplored.
Retinoids (compounds including vitamin A and its synthetic and naturally occurring analogs) are key molecules in cellular proliferation and differentiation [ 8].
The identified antisense transcripts in U. maydis provide a starting point for uncovering new roles for these molecules in cellular function.
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Furthermore, a critical molecule in cellular transformation as p21WAF has been proposed to be a selective target of Erk2 but not for ERK1 [50].
Ceramide is an important signaling molecule in cellular responses, including apoptosis [ 55].
"Molecule of the Month" addresses the importance of the featured molecule in cellular, tissue, organismal, and health contexts.
Our present work thus provides additional evidence of the essential role of the multifaceted CD26 molecule in cellular processes.
We used CD74-/ mice to examine the role of this molecule in cellular and in vivo inflammatory responses, using innate immune response-dependent models to avoid confounding by the role of MHC Ii in adaptive immunity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com