Sentence examples for genes in cellular from inspiring English sources

Moreover, knowledge of the normal developmental functions of these genes in cellular differentiation provides mechanistic insight into how these genes, when mutated, lead to cancer.

The screening of large-scale RNAi libraries has been used increasingly over the last years to identify the specific functions of genes in cellular pathways, networks and mechanisms.

Basonuclin likely coordinates functions of a subset of ribosomal RNA genes (rDNA) and a group of protein coding genes in cellular processes critical for the regulation of cell proliferation.

While we propose that both DIA1 and DIA1R encode a hydrophobic amino-terminal Golgi-retention motif, in the absence of known functional protein motifs and domains, ongoing studies on human DIA1 and DIA1R are required to determine the exact role(s) of these genes in cellular function, particularly the effects on cognitive function.

Further, it has been proposed that the genes in cellular networks are organized by a hierarchical and modular structure.

The differences would suggest different regulatory mechanisms of transcription and the functions of these genes in cellular processes.

However, expression of intratumor thymidylate synthase (TS), a significant gene in cellular proliferation, is associated with poor outcome to 5-FU-based chemotherapeutic regimens.

To gain a better understanding of the role of a particular gene in cellular physiology, it is often informative to examine the phenotypes of a deletion mutant lacking the gene of interest.

p53 is an important gene in cellular senescence, and p53expression is regulated by CPEB1.

Centrality is a class of network measurements used to determine the relative importance of a gene in cellular networks.

We follow gill tissue gene expression for genes active in cellular stress, cell maintenance, and apoptosis as well as plasma osmoregulatory, stress, and reproductive indices.