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If there is a problem with the filter mechanism, molecules can pass through it that might not normally and this often includes protein.
Mannitol pulls water out of the tightly packed cells lining the capillaries so that they shrink and pull away from one another, opening up gaps through which drug molecules can pass into the brain.
In particular, foetal blood glucose level depends on that of the mother because glucose molecules can pass through the placental barrier, and therefore it is reasonable to assume a similar fate for glucose analogue molecules like 18F-FDG molecules.
All these indicate that the membrane with pore size of 0.515~0.6 nm can be as a molecular sieve, where small H2 molecules can pass preferentially, whereas large CH4 is forbidden to penetrate.
Colloidally prepared Pt nanoparticles capped with organic ligands appear to be suitable as supported catalysts, and CO adsorption experiments have clearly shown that small molecules can pass through the ligand shell and adsorb on free areas of the Pt surface [38].
Small molecules can pass through these pores unaided, which is known as 'passive' transport.
Similar(48)
Molecules that can pass between cells coupled by gap junctions include inorganic salts, sugars, amino acids, nucleotides, and vitamins but not large molecules such as proteins or nucleic acids.
69 TKIs are small molecules which can pass through the plasma membrane and interfere with intracellular tyrosine kinase activity such as those of the VEGFRs.
The transition area, in combination with the internal structure of the basal body, is thought to function as a filter for the cilium, regulating the molecules that can pass into or out of the cilium.
Nevertheless, as a negatively charged molecule fondaparinux can pass the intestinal epithelial barrier after oral administration only partially.
The membranes of these columns have pores of distinct size that can retain viral particles, whereas smaller molecules and particle fragments can pass through the pores.
Related(20)
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molecules can think
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