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The arrangement and organization of cytoskeleton are the determinant factor in Young's modulus of cell bodies.

For instance, the mechanical disruption of cell membrane due to amyloid fibril [24] is ascribed to the elastic modulus of cell membrane being in the order of 100 kPa [25], which is about three orders of magnitude smaller than the elastic modulus of amyloid fibril [26].

Among various stimulatory models related to actin filaments, the elastic modulus of cell was estimated based on the bending of actin element in the open-cell foam model [12].

The observation of a power-law dependence of the creep response, or equivalently, the complex modulus of cell rheology, is consistent with the literature (26, 33, 35, 37, 47– 47).

The Young's Modulus of cell can be determined via analytical models or numerical simulation.

Similar(55)

The gel compressive modulus of cell-free PEG gels increased from 34 to 140 kPa with the incorporation of ChSA for similar degrees of swelling.

While the equilibrium tensile modulus of cell-free alginate did not change with time in culture, the constructs with highest cell density were 116% stiffer than cell-free controls after 2 weeks of culture.

Aligned scaffolds displayed significantly increased expression of tenomodulin compared to nonaligned scaffolds and exhibited aligned collagen fibrils throughout the full thickness, the presence of which may account for the increased yield stress and Young's modulus of cell-seeded aligned scaffolds along the axis of fiber alignment.

The force curve measurements of AFM were performed to estimate Young's modulus of cells.

The elastic modulus of cells is related to the content and arrangement of cytoskeletal elements especially actin fibers.

The mean ± SD values of elastic modulus of cells and gene expression levels of three endothelial specific genes were calculated for control and test groups.

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