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We will first discuss basic communication modules that confer cell-cell coordination in communities.
These different fibers allow a comparison of structure with function, because each silk has distinct mechanical properties and is composed of peptide modules that confer those properties.
Transported in the integrons, plasmids, and other cellular genetic modules that confer resistance, these snippets can be traded like baseball cards among microbes.
Similarly, the identification of biological modules that confer new functionalities, when assembled in different contexts, will drive the progress of SB (Schmidt and Pei, 2011).
Although neither the crystal nor solution structure is known for any of the E1A proteins, mutational analysis has clearly shown that the E1A proteins are organised as a collection of independent protein-binding modules that confer interaction with a number of cellular proteins (Gallimore and Turnell, 2001; Frisch and Mymryk, 2002; Berk, 2005).
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Heterologous dominant drug resistance markers, such as the kanMX module that confers resistance to G418 (Wach et al. 1994), provide some advantages over prototrophic biosynthetic markers for PCR-mediated gene disruption/deletion.
Initial genomic studies revealed that R. solanacearum strains have a substantial backbone of common housekeeping and virulence functions, but also carry a divergent set of genomic modules that likely confer distinct ecological phenotypes and host specificity [ 19, 24].
The P. parasitica genome also encodes proteins with two CBM modules (CBM18 and CBM50) that confer chitin binding [ 133, 134].
This review has surveyed recent advances of engineered biological systems that utilize cell-cell communication to program bacterial group behaviors, covering both the basic communication modules and functional gene circuits that confer desired community-based dynamic behaviors.
MAPK signaling modules provide multiple levels of regulation that confer signal amplification and specificity toward a desired outcome [ 4].
The properties of AuLOV extend the applicability of LOV domains as versatile design modules that permit fusion to effector domains via either the N- or C-termini to confer blue-light sensitivity.
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