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These scaffold proteins have cohesin modules that bind conserved dockerin modules on the enzymes.
All members of the LDL receptor gene family harbor at least one structurally highly similar extracellular ligand binding domain consisting of a series of negatively charged cysteine-rich Ca2+-chelating repeat modules that bind numerous ligands [14].
Protein modules that bind specific oligosaccharides are found across all kingdoms of life from single-celled organisms to man.
In addition, we hypothesized that important regulatory modules that bind transcription factors other than Ngn2 and Mash1 may be present surrounding the identified target genes.
Thus, the means of connecting microtubules to DNA may not be particularly important; provided the modules that bind DNA are linked to modules that can attach to microtubules, perhaps chromosome segregation can occur.
In other proteins, PAS domains serve as signaling modules that bind to small molecules and other proteins [14].
Similar(51)
Fluorescence microscopy can be used to detect crystalline cellulose by labelling TEs with CtCBM3-GFP (green fluorescent protein), a fluorescently labelled family-3 carbohydrate binding module that binds to cellulose (Lacayo et al. [2010]).
Histone lysine acetylation is enriched at active chromatin and the bromodomain (BD) is the protein module that binds acetylated lysines.
C-terminal to the FBXD is a variable recruitment module that binds to and delivers appropriate substrates for ubiquitylation.
The BRCT motifs function as a protein-protein interaction module that binds phosphorylated proteins involved in DNA repair, cell cycle control, chromatin remodeling, and transcription.
PDZ (PSD-95/Discs-large/ZO1) domains are interaction modules that typically bind to specific C-terminal sequences of partner proteins and assemble signaling complexes in multicellular organisms.
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