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Thus one can start with identifying the gene modules that associate with the topological, functional and disease.
The ASXM1 and ASXM2 domains are protein protein interaction modules that associate with NHRs and their cofactors.
By applying a network approach to multiple blood transcriptomics datasets, we have identified five coexpression PPI modules that associate with chronological age in humans.
Our future study includes the expansion of our study objectives to generate more detailed second-generation or third-generation regulatory networks for Nrf2 and Nfkb1 as more functional data emerge on these gene targets of interest and their interactions with coactivator/corepressor modules that associate with them.
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To identify modules that are more biologically meaningful, there are still two important aspects need to be considered: the miRNA-target relationships and identification of modules that associated with the pathogenesis of given disease.
These facts indicate that the region around the ASXH domain is a protein protein interaction module that associates with epigenetic regulators, such as BAP1 and KDM1A.
These results, combined with previous evidence that INTS3 regulates NABP2 at the mRNA level, suggested that the INTS3/NABP complexes might be protein modules that loosely associate with both the Integrator complex and Pol II to control transcription.
This can be demonstrated most clearly if the resources are included within course modules that integrate associated readings, discussion questions, assignments and related materials.
We identified five modules that significantly associated with meat quality.
Several modules that significantly associated with development stages were investigated and characterized by their functions.
Eigengenes that are adjacent to a clinical trait may correspond to pathways (modules) that are associated with the clinical trait.
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